A REVIEW ON HERBAL ANTHELMINTIC AGENTS

• Author Information

  Chandrakant Salhaita, P.K. Choudhury, Maya Sharma

• Chandrakant Salhaita, P.K. Choudhury, Maya Sharma
• A REVIEW ON HERBAL ANTHELMINTIC AGENTS

Abstract

Herbal anthelmintic drugs, derived from plants with potent bioactive compounds, have been utilized in traditional medicine for centuries to treat parasitic worm infections. These natural remedies are considered effective, affordable, and relatively safe alternatives to synthetic anthelmintics. Commonly used herbs such as Azadirachta indica (Neem), Artemisia absinthium (Wormwood), Allium sativum (Garlic), and Cucurbita pepo (Pumpkin seeds) exhibit broad spectrum activity against various helminths, including roundworms, hookworms, tapeworms, and pinworms. Their mechanisms of action primarily involve disrupting the metabolic processes of the parasites, causing paralysis, egg destruction, and boosting the host's immune response. Although evidence from in-vitro and animal studies supports their efficacy, clinical research in humans remains limited. Furthermore, while herbal anthelmintics are generally considered safe, improper use or excessive dosages may lead to adverse effects. This review emphasizes the therapeutic potential of herbal anthelmintics, their mechanisms, safety profiles, and the need for more rigorous clinical studies to validate their effectiveness.